MDR1 in immunity: friend or foe?

MDR1 in immunity: friend or foe?

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MDR1 is an ATP-dependent transmembrane transporter primarily studied for its sex shop arles role in the detoxification of tissues and for its implication in resistance of tumor cells to chemotherapy treatment.Several studies also report on its expression on immune cells where it plays a protective role from xenobiotics and toxins.This review provides an overview of what is known on MDR1 hindirochakkahaniya.com expression in immune cells in human, and its implications in different pathologies and their treatment options.